{"id":128717,"date":"2023-07-26T19:09:49","date_gmt":"2023-07-26T19:09:49","guid":{"rendered":"https:\/\/yogaesoteric.net\/?p=128717"},"modified":"2023-07-26T19:10:45","modified_gmt":"2023-07-26T19:10:45","slug":"rna-based-vaccine-technology-the-trojan-horse-didnt-contain-mrna","status":"publish","type":"post","link":"https:\/\/yogaesoteric.net\/en\/rna-based-vaccine-technology-the-trojan-horse-didnt-contain-mrna\/","title":{"rendered":"RNA-Based Vaccine Technology: The Trojan Horse Didn\u2019t Contain mRNA"},"content":{"rendered":"

It contains modRNA that genetically manipulates healthy cells<\/strong><\/p>\n

 <\/p>\n

A few years ago, the term \u201cmRNA\u201d was primarily confined to scientific circles and research papers. Back then, the use of messenger RNA (mRNA) seemed promising: It would teach cells to create a protein that would initiate an immune response against a specific pathogen.<\/p>\n

Today, many more of us have heard of mRNA, as both the Pfizer-BioNTech and Moderna covid vaccines use messenger ribonucleic acid, or mRNA, as the active ingredient. At least, that\u2019s what we\u2019ve been told.<\/p>\n

\"\"<\/p>\n

In fact, RNA-based vaccine technology utilizes modified RNA (modRNA), not mRNA. This applies to the covid vaccines and all vaccines currently in the research and development stages. Because mRNA is so fragile that the human immune system will destroy it within a few minutes, mRNA can\u2019t be effective on its own. Therefore, the current technology was made possible only after stabilizing mRNA; the result is modified RNA.<\/p>\n

Furthermore, modified RNA-based \u201cvaccines\u201d aren\u2019t vaccines but gene-based injections that force healthy cells to produce a viral protein. In this article, we will look at the uses and dangers of modRNA.<\/p>\n

Natural Infection and Conventional Vaccination<\/strong><\/p>\n

When you are infected naturally by a virus or have received a conventional vaccine, your immune system identifies virus-specific antigens from active or inactivated virus particles, respectively.<\/p>\n

The two main types of immune cells, T and B cells, behave differently. T cells identify infected cells and initiate apoptosis (the cell-killing process), while B cells produce antibodies that bind to the virus and thus prevent infection of other cells.<\/p>\n

There are various \u201cproteins\u201d\u2014called antigens\u2014on the surface of each virus. Your immune system can memorize more than one<\/a> of them. When the virus mutates and some proteins change, your immune system can still recognize and kill them. This is referred to as cross-immunity.<\/p>\n

Particularly in the case of respiratory disease, most pathogens are already prevented by the first natural barrier, the mucous membrane. This barrier, however, is bypassed when an intramuscular injection (such as the covid shot) is administered.<\/p>\n

\"\"
T and B cells behave differently depending on whether the host is infected naturally, with a conventional vaccine, or with an RNA-based injection.<\/figcaption><\/figure>\n

Results of Injections of modRNA<\/strong><\/p>\n

To protect against destruction by the immune system, modRNA is packaged in lipid nanoparticles<\/a> (LNPs) that, due to their small size and synthetic optimization, can easily overcome biological barriers and even reach vital cells in the heart and brain<\/a>.<\/p>\n

According to the concept of RNA-based injections, the antigen (here, the spike protein of SARS-CoV-2) is synthesized by our cells and presented at the cell surfaces, where it serves as a target for the generation of neutralizing antibodies.<\/p>\n

However, this mechanism is highly problematic.<\/p>\n

On the one hand, in addition to the desired neutralizing antibodies, non-neutralizing antibodies may be generated, resulting in antibody-dependent enhancement<\/a> (ADE). This process allows endocytosis of virus-antibody-complexes into the host\u2019s immune cells (i.e., macrophages), causing a weakening of the immune system.<\/p>\n

Put simply, non-neutralizing antibodies represent devils in disguise, making a person\u2019s body more susceptible to illness related to follow-up and booster injections.<\/p>\n

On the other hand, the viral spike protein, produced by the body\u2019s cells and presented at the cell surfaces, acts as a label, which transforms the recipient cell from friend to foe and causes the immune system to initiate the destruction of that cell by apoptosis.<\/p>\n

Furthermore, since covid RNA-based shots deliver only the genetic information for the spike protein of SARS-CoV-2, based on the Wuhan sequence, protection will be inferior to natural infection, which is known to establish cross-immunity. It does so by generating additional antibodies against another protein in the SARS-CoV-2 virus, the nucleocapsid protein.<\/p>\n

Given the virus variants\u2014Alpha, Beta, Gamma, Delta, and so on\u2014the original Wuhan sequence no longer exists. That means that antibodies produced by our immune system (based on an \u201cold\u201d virus sequence) are ineffective against the sequences of the new variants.<\/p>\n

This is yet another reason that RNA-based vaccine technology is and will always be inferior to natural infection, as viruses mutate far more rapidly than the pharmaceutical industry can produce new, adapted vaccines.<\/p>\n

The Dangers of Redundant Proteins<\/strong><\/p>\n

Proteins represent our body\u2019s building material and our metabolism\u2019s central molecules.<\/p>\n

For a functional metabolism, only essential proteins should be present in a distinct cell at a specific time. Proteins that are not required should be absent, as they will disrupt or even block the smooth running of the cell metabolism.<\/p>\n

Proteins, or mRNAs in healthy cells, can be compared to orchestra musicians: Harmony depends on various players pausing, not on every musician playing without stopping. Likewise, the absence of a specific protein\/mRNA plays an essential role in metabolism.<\/p>\n

As modRNAs are developed for longevity and maximal efficiency and (via lipid nanoparticles acting as natural exosomes) have access to all cells, they contradict the nature of mRNAs, which are cell-specific and short-lived. In our orchestra analogy, it would be like giving one musician a bass drum and instructing him to bang it from start to end, completely ignoring the piece of music being played.<\/p>\n

The C<\/strong>ovid mRNA Vaccine Is Made With modRNA<\/strong><\/p>\n

Messenger RNA carries the genetic information for the blueprint of one specific protein. The human body has different mechanisms to prevent mRNA from being translated and to support the degradation of mRNA that is no longer needed.<\/p>\n

\"\"
Messenger RNA carries the genetic information for the blueprint of one specific protein.<\/figcaption><\/figure>\n

A study published in<\/a> Science Advances<\/em> in 2017 reported that the expected lifetime of mRNA isn\u2019t hours to days, as previously assumed, but only minutes. However, the lifespan of modRNA is long.<\/p>\n

Therefore, the basic idea of RNA-based injections contradicts the nature of mRNA in all aspects, as modRNA has been optimized for maximum translation efficiency and maximum lifespan. There is no reason that any cell in our body, including vital cells in the heart and brain, should produce as many molecules of a foreign viral protein as possible for as long as possible\u2014which, in addition, transforms this cell into a target to be attacked and destroyed by our immune system.<\/p>\n

To ensure mRNA can stay in the recipient\u2019s body longer, the covid vaccine makers modified the mRNA to use modRNA.<\/p>\n

The modRNA: A Trojan Horse That May Be Worse Than the Disease<\/strong><\/p>\n

\"\"<\/p>\n

\"\"
How RNA-based injections work.<\/figcaption><\/figure>\n

Even though modRNA encodes for the spike protein of SARS-CoV-2, the aim was never to mimic viral RNA, which our immune system would immediately destroy, but to adapt it to the structure of human mRNA.<\/p>\n

The \u201cfake\u201d mRNA\u2014modRNA\u2014can have three problems:<\/p>\n

1. It Can Increase Errors While Making Spike Proteins<\/strong><\/p>\n

Of note, the synthetic methyl-pseudouridine, which replaces the natural uridine, has been reported to increase the transcriptional error rate<\/a>, namely one error every 4,000 nucleotides\u2014one error per every synthesized \u201cvaccine\u201d molecule.<\/p>\n

2. Active Ingredients Vary Greatly by Different Batches<\/strong><\/p>\n

Another factor of concern is the unusually broad \u201ctolerance level\u201d of the active ingredient. The modRNA concentration ranges from 0.37 milligrams\/milliliter (mg\/ml) to a maximum of 0.63 mg\/ml (pdf<\/a>), as shown in the European Medicines Agency (EMA) Assessment Report<\/em>. Such a variation is highly unusual for a drug.<\/p>\n

Furthermore, the vaccine requires only a minimum of 50 percent of modRNA to be present as intact molecules with a complete sequence, which means there can be up to a 3.4-fold variation of the active substance present in different batches.<\/p>\n

Since one dose of Comirnaty (Pfizer-BioNTech) represents 0.3 ml containing 30 micrograms of active substance, approximately 13 trillion modRNA molecules will be transferred into the body per injection.<\/p>\n

And the third problem is an even more significant concern.<\/p>\n

3. This modRNA May Be Incorporated Into the Human Genome<\/strong><\/p>\n

According to the political narrative, mRNA from covid vaccines doesn\u2019t enter the cell nucleus, where human DNA is located. The narrative also insists that covid vaccines don\u2019t contain reverse transcriptase, thereby entirely precluding reverse transcription of mRNA into DNA with subsequent transport into the nucleus and incorporation into the host genome. Two publications have refuted this.<\/p>\n

Liguo Zhang and colleagues added the RNA genome of SARS-CoV-2 in the absence of reverse transcriptase to human embryonic kidney (HEK293T) cells. They observed that the cultured cells reverse-transcribed<\/a> the viral RNA into DNA and integrated this DNA into the cell\u2019s genome.<\/p>\n

In their PNAS<\/em>-published study, the authors suggested a mechanism mediated by LINE1 (Long Interspersed Nuclear Element-1), which can act as an endogenous reverse transcriptase. As LINE1 accounts for approximately 17 percent of the human genome, it\u2019s highly likely that reverse transcription of the administered modRNA is possible.<\/p>\n

In their study published in Current Issues in Molecular Biology<\/em>, Markus Ald\u00e9n and colleagues added the Pfizer-BioNTech covid RNA vaccine (BNT162b2) to human liver (Huh7) cells and observed reverse transcription into DNA<\/a> in as short a period as six hours.<\/p>\n

The DNA sequence unique to BNT162b2 was demonstrated within the cultured cells\u2019 genome, confirming the integration of reverse-transcribed modRNA into DNA. In addition, an increased nucleus distribution of LINE1 has been observed, corroborating a LINE1-mediated integration mechanism.<\/p>\n

Critically, sperm is known to contain high levels of LINE1 (pdf<\/a>).<\/p>\n

Although earlier findings are based on studies in cell cultures, insertion into the human genome is possible, a fact that has already been impressively proven by evolution, as it\u2019s known that up to 8 percent of the human genome doesn\u2019t originate from our ancestors but from retroviruses<\/a>. As previously shown, reverse transcription with subsequent genome integration is also possible for SARS-CoV-2 as a single-stranded RNA virus using LINE1.<\/p>\n

The modRNA and Its Secret Byproducts<\/strong><\/p>\n

The so-called RNA-based vaccines from Pfizer-BioNTech and Moderna contain DNA impurities in addition to the active substance modRNA.<\/p>\n

As stated in the EMA Assessment Report<\/em>, \u201cthe BNT162b2 [Pfizer vaccine] active substance is manufactured by in vitro transcription using a linear DNA template, produced via plasmid DNA from transformed Escherichia coli cells<\/em>.\u201d<\/p>\n

\"\"<\/p>\n

In a recent study<\/a>, researchers demonstrated that the DNA contamination in both the Pfizer-BioNTech and Moderna injections averages 9.1 nanograms\/microliter (ng\/\u00b5l) mean DNA concentration versus 33.4 ng\/\u00b5l mean RNA concentration.<\/p>\n

This means that approximately one-quarter (9.1 \/ 33.4 x 100 = 27.3 percent) of the nucleic acids in the analyzed vials can be attributed to DNA impurities. At the same time, the active substance modRNA represents the remaining three-quarters.<\/p>\n

Plasmids are circular DNA molecules that can replicate by themselves. It\u2019s assumed that this isn\u2019t the case with linearized DNA. Although the proportion of circular, replication-competent DNA plasmids versus linear DNA templates for the in vitro transcription of modRNA is still unknown, the DNA concentration isn\u2019t only several orders of magnitude over the limit of 330 nanograms\/milligram (ng\/mg), as specified by the EMA, but also implies that billions of DNA molecules are transferred per shot of the RNA-based vaccines.<\/p>\n

This has the following two consequences:<\/p>\n

    \n
  1. Plasmids<\/strong> generally comprise sequences encoding for antibiotic resistance; this is essential for the production process to avoid the reproduction of other bacteria, which didn\u2019t contain the sequences encoding for the spike protein. In this instance, kanamycin can be exchanged with other bacteria, increasing the risk of developing multiresistant germs.<\/li>\n
  2. DNA impurities<\/strong> have the potential to incorporate into the recipient cell genome and, in consequence, may cause mutations that are followed by aberrant gene expression. Reverse transcription by LINE1 is no longer a mandatory step for the integration of spike protein-encoding sequences into the genome. Reverse transcription of modRNA into DNA followed by genome integration is the long way. However, an additional short way may exist\u2014namely, direct integration of DNA contaminants. Both sequences (RNA and DNA) encode for the spike protein.<\/li>\n<\/ol>\n

    Finally, the process of in vitro<\/em> transcription will also result in truncated RNA species as product-related impurities, which will result in the synthesis of imperfect spike proteins.<\/p>\n

    Summary<\/strong><\/p>\n

    The administered covid mRNA vaccine is modRNA, which contradicts the nature of mRNA.<\/p>\n

    The modRNA forces perfectly healthy cells to produce a viral protein, transforming these cells from friend to foe. Therefore, RNA-based injections aren\u2019t vaccines at all but genetic manipulations. This certainly challenges the political narrative of a powerful next generation of vaccines.<\/p>\n

    The harmful consequences are still far from being understood. Numerous adverse effects have already become obvious, shifting the cost-benefit ratio of RNA-based vaccine technology for mass application unequivocally to the malefic side.<\/p>\n

    Author: Klaus Steger, Ph.D., a molecular biologist with a research focus in the genetic and epigenetic regulation of gene expression. Over the past 30 years, he headed several gene technology laboratories regularly applying RNA-based technologies. He served as a professor of anatomy and cell biology at the University of Giessen, Germany, for 23 years before retiring this year. He holds a doctorate in natural sciences from the University of Regensburg.<\/em><\/p>\n

     <\/p>\n

    yogaesoteric
    \nJuly 26, 2023<\/strong><\/p>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

    It contains modRNA that genetically manipulates healthy cells   A few years ago, the term \u201cmRNA\u201d was primarily confined to scientific circles and research papers. Back then, the use of messenger RNA (mRNA) seemed promising: It would teach cells to create a protein that would initiate an immune response against a specific pathogen. Today, many […]<\/p>\n","protected":false},"author":5,"featured_media":128733,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[1102],"tags":[],"class_list":["post-128717","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-risks-for-your-health-4260-en-health-en"],"_links":{"self":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts\/128717","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/comments?post=128717"}],"version-history":[{"count":1,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts\/128717\/revisions"}],"predecessor-version":[{"id":128736,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts\/128717\/revisions\/128736"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/media\/128733"}],"wp:attachment":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/media?parent=128717"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/categories?post=128717"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/tags?post=128717"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}