{"id":241508,"date":"2026-07-28T17:03:23","date_gmt":"2026-07-28T17:03:23","guid":{"rendered":"https:\/\/yogaesoteric.net\/?p=241508"},"modified":"2026-07-28T17:03:23","modified_gmt":"2026-07-28T17:03:23","slug":"beekeepers-dont-get-cancer","status":"publish","type":"post","link":"https:\/\/yogaesoteric.net\/en\/beekeepers-dont-get-cancer\/","title":{"rendered":"\u201cBeekeepers Don\u2019t Get Cancer\u201d"},"content":{"rendered":"<p>Recently an apiarist told me about an old wives\u2019 tale. She said the scuttlebutt in the beekeeping world is that \u201c<em>beekeepers don\u2019t get cancer<\/em>.\u201d<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-241509\" src=\"https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/bee1.png\" alt=\"\" width=\"560\" height=\"373\" srcset=\"https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/bee1.png 1080w, https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/bee1-300x200.png 300w, https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/bee1-1024x683.png 1024w, https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/bee1-768x512.png 768w\" sizes=\"auto, (max-width: 560px) 100vw, 560px\" \/><\/p>\n<p>Many anti-cancer protocols insist on zero sugar and no sweeteners of any kind, whether natural or artificial. But this apiarist is a firm believer in the healing power of honey, as well as in the immune benefits of bee stings.<\/p>\n<p>All of this piques my curiosity. Is it really true that beekeepers don\u2019t get cancer? And if beekeepers don\u2019t get cancer, why not? Is it the honey? Is it the bee stings? Is it that they\u2019re spending most of their days outside in the healing sunshine, soaking up the vitamin D?<\/p>\n<p>Is it that they\u2019re also digging in the dirt a lot and we know getting down and dirty \u2013 playing in the dirt, keeping animals, growing organic food \u2013 helps us avoid chronic diseases, autoimmune disorders, and cancer, at least according to paediatric neurologist Maya Shetreat-Klein, M.D., author of <em>The Dirt Cure<\/em>?<\/p>\n<p>Is it that most beekeepers usually live on farms, eat fresh, whole foods, and generally follow a more active and healthier lifestyle than many modern-day humans who eat ultra-processed foods and live sedentary lives?<\/p>\n<p>Is it something else entirely?<\/p>\n<p>Researching human health and longevity is notoriously complicated. A cure for one person with cancer may have no effect on another patient\u2019s disease. It may even accelerate cancer growth in someone else with the same diagnosis.<\/p>\n<p>So, I can\u2019t give you a definitive answer about beekeepers and cancer. Like with many health questions, I\u2019m not sure what I think. But I can share with you some of what my research has revealed.<\/p>\n<p><strong>Fuzzy chemists<\/strong><\/p>\n<p>Bees aren\u2019t just adorable and wonderful and good for the planet in so many ways. They\u2019re also little fluffy chemists and builders.<\/p>\n<p>They make something called propolis \u2013 a sticky, resinous material also known as \u201cbee glue.\u201d They use this propolis to seal cracks in their hives, protect the colony from predators, and help keep certain non-beneficial microbes out of the colony, according to <a href=\"https:\/\/scienceinsights.org\/what-is-bee-propolis-benefits-uses-and-safety\/\"><em>ScienceInsights.org<\/em><\/a>.<\/p>\n<p><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2013\/697390\">Propolis is chemically fascinating<\/a>. Its composition modifies depending on where the bees live, which flowers and other plants the bees are frequenting, and the season.<\/p>\n<p>We have interesting data showing that propolis can be protective against cancer, and may also be an effective anti-cancer bee product for treating cancer patients. This may in part be due to a compound found in propolis called CAPE: caffeic acid phenethyl ester.<\/p>\n<p><strong>Why caffeic acid phenethyl ester (CAPE) matters<\/strong><\/p>\n<p>In a peer-reviewed scientific article <a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.93.17.9090\">published in 1996<\/a>, a team of scientists from the University of Texas found that CAPE blocked activation of NF-\u03baB. NF-\u03baB activation is an inflammatory factor involved in immune signalling, inflammation, cell survival, and cancer-related stress responses.<\/p>\n<p>If I may simplify: blocking NF-\u03baB activation is good and has the potential to help fight against cancer. NF-\u03baB matters because some cancer cells use inflammatory survival programs to avoid dying. For example, in 2001 scientists <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2193582\/\">discovered<\/a> that NF-\u03baB activity is required for tumour-cell survival in activated B cell-like diffuse large B cell lymphoma.<\/p>\n<p>CAPE has also been studied in gastric epithelial cells exposed to <em>Helicobacter pylori<\/em>, the bacterium linked to ulcers and gastric cancer. In a <a href=\"https:\/\/www.researchgate.net\/publication\/7520096_Caffeic_acid_phenethyl_ester_modulates_Helicobacter_pylori-induced_nuclear_factor-kappa_B_and_activator_protein-1_expression_in_gastric_epithelial_cells\">2005 study<\/a>, published in the <em>British Journal of Pharmacology<\/em>, Egyptian scientists found that CAPE inhibited <em>H. pylori<\/em>-induced NF-\u03baB and AP-1 DNA-binding activity in a dose-dependent way. That study also found that CAPE reduced <em>H. pylori<\/em>-induced cell proliferation, inflammatory cytokines, and COX-2 expression.<\/p>\n<p>In an earlier study on <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/jf034729d\">colon cancer<\/a>, a team of researchers in Taiwan found that CAPE inhibited capillary-like tube formation, reduced invasion by CT26 colon adenocarcinoma cells, lowered MMP-2 and MMP-9 activity, and reduced VEGF production in mice.<\/p>\n<p>VEGF stands for vascular endothelial growth factor. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1043466625000559\">VEGF promotes the formation of new blood vessels<\/a> that then feed nutrients to cancer cells. In the 2003 Taiwanese study when CAPE was given intraperitoneally (that is, administered via entry into the small bowel), it reduced pulmonary metastasis and lowered blood levels of VEGF.<\/p>\n<p>CAPE has also been studied in breast cancer cells. In 2004, scientists in Japan found that CAPE appeared to help push some cancer cells from survival mode toward self-destruct mode.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-241515\" src=\"https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/propolis-bee2.jpg\" alt=\"\" width=\"560\" height=\"388\" srcset=\"https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/propolis-bee2.jpg 593w, https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/propolis-bee2-300x208.jpg 300w\" sizes=\"auto, (max-width: 560px) 100vw, 560px\" \/><\/p>\n<p>At the same time, another study, published in 2009, found that CAPE was eliminated rapidly after intravenous administration in rats, with a half-life of only about 21 to 27 minutes.<\/p>\n<p>Questions remain: What does it mean that CAPE has such a short half-life <em>in vivo<\/em>? Are these studies biologically relevant to humans struggling with cancer? What\u2019s the best and most effective way to get CAPE into the human body? Does it do anything when taken orally as opposed to being administered intravenously? What kind of dosing do we need to give a human patient in order for it to be effective? And how do we source the propolis that has the largest concentrations of anti-cancer properties?<\/p>\n<p>So we know that propolis in general and CAPE in particular can help mitigate cancer-induced inflammatory, apoptotic, angiogenic, and invasive pathways. Might this be one reason beekeepers don\u2019t get cancer as often as non-beekeepers?<\/p>\n<p><strong>And then there\u2019s the bee venom\u2026<\/strong><\/p>\n<p>When I met with the apiarist recently, she did a sting test on me. Epi-pen and antihistamines in hand, she put a bee on my abdomen and had it sting me near my liver.<\/p>\n<p>\u201c<em>I enjoy getting stung by bees<\/em>\u201d said no sane person ever. It hurt. I also felt bad for the bee, whose life was then forfeit. And I had a full-blown immune reaction, with swelling and redness and itching that started the next day and lasted for nearly a week. No fun.<\/p>\n<p>Pain notwithstanding, bee venom is touted as a powerful anti-inflammatory. It contains a mixture of bioactive compounds, has two peptides that are thought to be beneficial to human health. A peptide is a short string of amino acids and a building block of protein. The two peptides are:<\/p>\n<ul>\n<li>Melittin, a 26-amino-acid peptide<\/li>\n<li>Apamin, an 18-amino-acid peptide<\/li>\n<\/ul>\n<p>Melittin is a main component of honeybee venom. It interacts with cell membranes and can rupture cells. Cancer cells don\u2019t like having their membranes disrupted.<\/p>\n<p>In 2020, an interesting and important <a href=\"https:\/\/www.nature.com\/articles\/s41698-020-00129-0\">study<\/a> on bee venom\u2019s effects on cancer was published in the prestigious journal <em>Nature<\/em>. An international team of scientists based in Australia and the United States found that honeybee venom suppressed growth factor receptor activation in HER2-enriched and triple-negative breast cancer cells.<\/p>\n<p>Melittin was especially potent in aggressive breast cancer subtypes. It appeared to suppress EGFR and HER2 phosphorylation, interfering with downstream PI3K\/Akt and MAPK signalling.<\/p>\n<p>Triple-negative breast cancer is notoriously hard to treat. HER2-enriched cancers are as well. While that study didn\u2019t show that bee stings cure breast cancer, it did find that melittin is biologically potent and mechanistically interesting.<\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0041008X11004017\">Another study<\/a> on ovarian cancer, published in 2012, found that bee venom inhibited the growth of SKOV3 and PA-1 ovarian cancer cells, increased death receptor expression, and inhibited JAK2\/STAT3 signalling.<\/p>\n<p>I think it\u2019s fair to assume that beekeepers get stung by bees regularly, and that this is likely another reason for why they don\u2019t get cancer as often as the rest of us.<\/p>\n<p>But the best avenue for melittin as a cancer treatment is probably not having cancer patients get stung over and over again by bees. Instead, scientists would need to develop a safe and effective way to safely deliver melittin so that it can destroy cancer cells without doing excessive harm to the human host.<\/p>\n<p>One way to do this may be by suspending the melittin in microscopic globules of oil. Scientists in China examined whether melittin-lipid nanoparticles designed to target lymph nodes could trigger a systemic anti-tumour immune response.<\/p>\n<p>Those experiments, <a href=\"https:\/\/www.nature.com\/articles\/s41467-020-14906-9\">published in <\/a><a href=\"https:\/\/www.nature.com\/articles\/s41467-020-14906-9\"><em>Nature Communications<\/em><\/a> in 2020, found that \u03b1-melittin nanoparticles promoted tumour antigen release in place, activated antigen-presenting cells in lymph nodes, increased antigen-specific CD8+ T-cell responses, and inhibited both primary and distant tumour growth in a B16F10 melanoma mouse model. In that mouse model, \u03b1-melittin nanoparticles produced dramatic inhibition of both primary and distant tumours.<\/p>\n<p>This study seems particularly important to me, perhaps because I have metastatic melanoma. It suggests that when melittin is packaged and delivered intelligently, it can become a local immune activator and an effective way to inhibit tumour growth.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-241512\" src=\"https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/honey.jpg\" alt=\"\" width=\"560\" height=\"373\" srcset=\"https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/honey.jpg 2560w, https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/honey-300x200.jpg 300w, https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/honey-1024x683.jpg 1024w, https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/honey-768x512.jpg 768w, https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/honey-1536x1024.jpg 1536w, https:\/\/yogaesoteric.net\/wp-content\/uploads\/2026\/07\/honey-2048x1366.jpg 2048w\" sizes=\"auto, (max-width: 560px) 100vw, 560px\" \/><\/p>\n<p><strong>What about honey itself?<\/strong><\/p>\n<p>Honey is a chemically complex substance that contains hundreds of different compounds. However, not all honey is created equal.<\/p>\n<p>Many varieties of honey \u2013 like so many other foods \u2013 have been found to be contaminated with known carcinogens, and also a lot of the store-bough honey is counterfeit. It is best to buy raw honey from a known source.<\/p>\n<p>The mother of all honeys, known for its healing properties and used even in conventional medicine, is Manuka honey. It comes from bees that pollinate the Manuka tree, <em>Leptospermum scoparium<\/em>, a flowering tree in the myrtle family native to New Zealand.<\/p>\n<p>A key compound in Manuka honey is methylglyoxal, or MGO. In a <a href=\"https:\/\/www.researchgate.net\/publication\/323116159_Methylglyoxal_in_Manuka_Honey_-_Correlation_with_Antibacterial_Properties\">2009 Czech study<\/a> of 61 Manuka honey samples, MGO levels ranged from 189 to 835 mg\/kg, and antibacterial activity rose in close correlation with MGO concentration.<\/p>\n<p>The Czech scientists concluded that MGO was the dominant bioactive compound responsible for the characteristic antibacterial properties of Manuka honey above about 150 mg\/kg.<\/p>\n<p>Antibacterial properties, check. Wound healing potential, check. (When an 82-year-old friend went to the doctor the other day for a wound on his leg that would not heal, they slathered the wound with Manuka honey and put a dressing over it.)<\/p>\n<p>What about anti-cancer properties?<\/p>\n<p>In a <a href=\"https:\/\/www.frontiersin.org\/journals\/oncology\/articles\/10.3389\/fonc.2021.645686\/full\">2021 review<\/a> article, scientists in Italy explained that MGO has a dual role in tumour progression. At high levels, MGO can be cytotoxic and push cells toward apoptosis.<\/p>\n<p>Apoptosis is programmed cell death. It\u2019s what we want healthy cells to do when they\u2019re misbehaving. When you have cancer, this normal, life-saving apoptosis shuts off. Cancer cells have unchecked growth, which is a problem since they will eventually grow themselves out of existence by killing the host.<\/p>\n<p>At the same time, according to the Italian researchers, at lower levels, cancer cells may adapt to MGO stress in ways that actually encourage and support tumour progression, the opposite of what we want a cancer treatment to do.<\/p>\n<p>\u201c<em>Poking the bear<\/em>\u201d is how an ozone engineer named Steve, who has dedicated the second half of his career to helping people fight cancer, describes sub-therapeutic cancer treatment dosing.<\/p>\n<p>You don\u2019t want to wake the bear up and make him angry. You want to usher the bear out of your body and make sure it never returns.<\/p>\n<p><strong>A 2024 Manuka honey breast cancer study<\/strong><\/p>\n<p>Natural health advocates make a huge to do about manuka honey.<\/p>\n<p>A <a href=\"https:\/\/www.mdpi.com\/2072-6643\/16\/14\/2369\">2024 preclinical study<\/a> done by a team of scientists at UCLA reported that Manuka honey inhibited human breast cancer progression in laboratory and animal models.<\/p>\n<p>This study used human breast cancer cells transplanted into mice. In MCF-7 breast cancer cells, Manuka honey inhibited proliferation at 0.3 to 5.0 percent methylglyoxal (MGO). At 2.5 percent MGO, it reduced proliferation of MCF-7 cancer cells but not non-malignant human mammary epithelial cells. It also stimulated apoptosis, increased PARP cleavage, activated AMPK, inhibited AKT\/mTOR signalling, and reduced phosphorylated STAT3.<\/p>\n<p>In mice with established MCF-7 tumours, orally administered Manuka honey significantly inhibited tumour growth. The study reported an 84 percent reduction in established tumour growth.<\/p>\n<p>This UCLA study wasn\u2019t a randomized clinical trial in women with breast cancer. And it doesn\u2019t prove that eating Manuka honey is an effective treatment for breast cancer. But it does suggest that Manuka honey may be a powerful way to help breast cancer patients heal.<\/p>\n<p><strong>So, is it good to eat honey and use bee products if you have cancer?<\/strong><\/p>\n<p>For over a year after I was diagnosed with ocular melanoma, I ate nothing sweet. No refined sugar, date sugar, or coconut sugar. No maple syrup. No honey. I did eat some fruit, including blueberries, but I avoided over-ripe bananas, raisins, dates, and sweet apples.<\/p>\n<p>Now I eat a little local honey.<\/p>\n<p>When it comes to bees and cancer, here are my take-aways:<\/p>\n<ul>\n<li>Bee-derived compounds show potential in treating cancer.<\/li>\n<li>Getting stung by bees is also likely beneficial to the immune system (as long as you don\u2019t have an anaphylactic reaction).<\/li>\n<li>Manuka honey is biologically active, appears to have several anti-cancer properties, and has shown promise in preclinical breast cancer rodent studies.<\/li>\n<li>Honey and bee-derived compounds may be effective cancer-busters \u2013 especially if scientists, clinicians, and patients can figure out the best delivery methods, proper dosing, and safety issues.<\/li>\n<\/ul>\n<p>In the meantime, I don\u2019t think I\u2019ll become a beekeeper in this lifetime. But I am working very hard to not die from stage four metastatic melanoma, and I will keep drawing and sending my love to bees.<\/p>\n<p><em>Author: Jennifer Margulis, Ph.D.<\/em><\/p>\n<p><em>\u00a0<\/em><\/p>\n<p><strong>yogaesoteric<br \/>\nJuly 28, 2026<\/strong><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Recently an apiarist told me about an old wives\u2019 tale. She said the scuttlebutt in the beekeeping world is that \u201cbeekeepers don\u2019t get cancer.\u201d Many anti-cancer protocols insist on zero sugar and no sweeteners of any kind, whether natural or artificial. But this apiarist is a firm believer in the healing power of honey, as [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[1317],"tags":[],"class_list":["post-241508","post","type-post","status-publish","format-standard","hentry","category-healthy-food-4260-en-health-en-health-en"],"_links":{"self":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts\/241508","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/comments?post=241508"}],"version-history":[{"count":1,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts\/241508\/revisions"}],"predecessor-version":[{"id":241518,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts\/241508\/revisions\/241518"}],"wp:attachment":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/media?parent=241508"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/categories?post=241508"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/tags?post=241508"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}