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<\/p>\nGarlic contains a substance that is particularly effective in encounters with even the hardiest bacterial strains. Aggressive multi-resistant infections constitute an increasing health problem all over the world. Bacteria are developing resistance at an alarming pace, so new pharmaceuticals that can combat this threat are in great demand.<\/p>\n
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\u201cWe know that there is a potent compound in the garlic plant that neutralises resistant bacteria by paralysing their communication system. My PhD thesis demonstrates that ajoene \u2013 the substance present in garlic \u2013 specifically prevents the bacteria from secreting the toxin rhamnolipid which destroys white blood cells in the body. White blood cells are indispensable because they play a crucial role in the immune defence system, not only warding off infection, but also killing bacteria<\/em>,\u201d explains Tim Holm Jakobsen from the Faculty of Health and Medical Sciences.<\/p>\n A tough sheath of biofilm<\/strong><\/p>\n When bacteria clump together in what is known as biofilm \u2013 where they surround themselves with a tough film of organic materials \u2013 they become resistant to antibiotics. Researchers have been devoting much of their attention to Pseudomonas aeruginosa<\/em> bacteria, which cause infections in patients with chronic leg ulcers, for example, and in the lungs of patients suffering from cystic fibrosis.<\/p>\n \u201cAjoene supports and improves treatment with conventional antibiotics. We have clearly demonstrated this on biofilm cultivated in the laboratory and in trials involving mice. When we add antibiotics to biofilm they have very little effect, and ajoene alone barely makes any difference. It is only when the two are combined that something significant occurs<\/em>,\u201d explains Tim Holm Jakobsen.<\/p>\n Combination treatment with ajoene and antibiotics kills more than 90 per cent of the normally virulent biofilm. From a technical perspective, the ajoene blocks the communication system \u2013 known as Quorum Sensing<\/em> \u2013 in the bacteria, which is used for purposes including creating infection.<\/p>\n Chemists outstrip nature<\/strong><\/p>\n A large number of natural substances have proved extremely effective as medicines; taxol from the yew tree is used to treat breast cancer, for example, while artemisinin from sweet wormwood is effective against malaria. However, to improve on the original substances from nature \u2013 and to assure sustainable pharmaceutical production \u2013 researchers are working to augment natural materials through chemical synthesis.<\/p>\n \u201cGarlic contains so little ajoene that you would need to eat around 50 a day to achieve the desired effect. This means we have to pick up the ball from Mother Nature and run with it,<\/em>\u201d says Tim Holm Jacobsen, who thinks that the pharmaceutical industry will be quick to turn its attention to producing of the natural substance to which the research group currently holds the patent.<\/p>\n \u201cThere\u2019s a lot of money in pharmaceuticals for treating chronic illnesses such as diabetes, but if we are to win the race against bacteria, we need to bring new antibiotics into play. Nature is a great starting point for developing medicines \u2013 two-thirds of all new pharmaceuticals are based on natural substances<\/em>,\u201d concludes Tim Holm Jakobsen.<\/p>\n <\/p>\n yogaesoteric<\/strong> Garlic contains a substance that is particularly effective in encounters with even the hardiest bacterial strains. Aggressive multi-resistant infections constitute an increasing health problem all over the world. Bacteria are developing resistance at an alarming pace, so new pharmaceuticals that can combat this threat are in great demand. \u201cWe know that there is a potent […]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[1317],"tags":[],"class_list":["post-83667","post","type-post","status-publish","format-standard","hentry","category-healthy-food-4260-en-health-en-health-en"],"_links":{"self":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts\/83667","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/comments?post=83667"}],"version-history":[{"count":1,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts\/83667\/revisions"}],"predecessor-version":[{"id":83671,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/posts\/83667\/revisions\/83671"}],"wp:attachment":[{"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/media?parent=83667"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/categories?post=83667"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yogaesoteric.net\/en\/wp-json\/wp\/v2\/tags?post=83667"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nJune 2, 2022<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"